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Ean Moody



2010.05.04 21:29:00

Researchers at UCLA have imaged a virus at high enough resolution to essentially "view" its constituent atoms, according to a report in the April 30 edition of the journal Cell. This is the first published report of a biological imaging at such a high resolution.

Using a new technology known as “cryo-electron microscopy” to image the virus at a resolution of 3.3 angstroms the research team captured the moment of cellular infection by a specific non-envelope virus. This opens the way for a wide variety of new biological studies according to Xing Zhang, UCLA professor of microbiology, immunology, and molecular genetics, who lead the research team.


  
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2010.04.07 22:26:45

This review by "Morgan" at Morganonscience.com shows off the features and benefits of the iPad from the perspective of a scientific researcher. It touches on a number of key features and usability issues that are not typically considered by the more technology-oriented blogs.

Click Here to watch the full video review


  technology | news
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2010.01.29 01:37:48

From Scienceblog:

The Micro-western array opens
up a new horizon of mass-analysis for proteins.

A major development in the world of immunohistochemistry, the "micro-western array" allows dozens or even hundreds of proteins to be measured and compared simultaneously. It was described in the journal Nature Methods this week.

Richard B. Jones, senior author and assistant professor at the University of Chicago, compare
d the new technology to "turning on the lights" in a darkened room instead of bumping into things one step at a time.


  innovation | technology | histology | microscopy
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2010.01.23 02:14:16

From Slashdot and bbc.co.uk,

Scientists from the International Cancer Genome Consortium have successfully decoded the complete genetic codes of two of the most common types of cancer, Melanoma and lung cancer.

The study found that a typical melanoma contains 30,000 or more genetic code errors, with most resulting from exposure to sunlight. The study also revealed that up to 25,000 errors exist in lung cancer, many of which can be the result of exposure to cigarette smoke. From the article: "...  the experts estimate a typical smoker acquires one new mutation for every 15 cigarettes they smoke. "

An idea brought forth in the study is that genetic cataloging of cancers might become routine when they are discovered in a patient. How do you think this might affect histology practices in the future? Could you see genetic scanning and sequencing as a part of the histological examination process?

Read the full article here


  
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2010.01.12 23:01:42

From BoingBoing

The Olympus Bioscapes International Digital Imaging Competition is an annual biological microscopy competition. First Prize is a selection of Olympus camera and microscope equipment worth $5,000. The contest is closed for this year, and the winners have been announced. The images are brilliant fluorescent miniature landscapes and portraits. 

The image shown is a water flea, photographed by  Dr. Jan Michels, from the University of Kiel in Germany.

You can view the full gallery here.

If any of our customers have their own images they would love to share with the world, submit them in the comments of this post.


  photography | art | microscopy | histology
Comments 0 Hits: 389  

2009.12.16 02:49:34

From BoingBoing

If you're looking for an interesting and amusing way to spice an upcoming holiday party, the amazing culinary artists at NotSoHumblePie cooking blog have created recipes for an assortment of great science-themed cookies. These are sure to bring a smile to the face of any technician, doctor, or scientist during the holidays.

Pictured are Gel Electrolysis Squares, but their scientific list also includes Petri Dish Cookies, Gingerbread Scientists, A Periodic Table, and Lab Mice. Has anyone ever made stained-cell cookies? Or shortbread slides?


  histology | mercedes medical | community | funny | cookies
Comments 0 Hits: 389  

2009.12.11 19:16:37

From Dark Daily

“A new chip, developed at Stanford University's Center for Magnetic Nanotechnology, has the potential to detect any of seven different types of cancer in their early developmental stages. Magnetic technologies give the biomarker chips increased sensitivity as compared to traditional fluorescent detection methodology. In some cases, this could be as much as 400 times more sensitive.


The device consists of 64 magnetic sensors known as Spin Valves. Each of these sensors is coated with a cancer-specific antibody, which will attach to a specific cancer protein. Using two sets of specially prepared antibodies, the tumor proteins are bound to magnetic nanoparticles so that the magnetic sensors can detect the cancerous proteins.

  innovation | technology | cancer | diagnostics
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2009.12.07 22:32:19

From UCSD

The brain of famous amnesiac patient H.M. is currently being sliced into 3,000 giant histological sections to be mounted and stained on glass plates. The entire process is being broadcast live at "The Brain Observatory", a site hosted by UC San Diego.

Doctors at UCSD are performing a massive 30-hour microtome session in order to section the entire brain. The brain has been frozen into a gelatin medium for the process as opposed to embedded in paraffin.

H.M. was an amnesiac patient who developed severe anterograde amnesia at the age of 16, after a surgery intended to cure his lifelong epilepsy. This meant he was incapable of forming new long-term memories, though he retained the ability to learn certain types of new information and skills. The study of his condition helped develop a number of theories in the field of cognitive neuropsychology,  a branch of psychology that aims to correlate physical structures of the brain to psychological functions.


  microscopy | news | medical
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2009.12.04 21:37:29

From ScienceBlog

Evidence for Green Tea as a cancer prevention method continues to grow, though scientists are not yet ready to officially endorse it for that purpose. The results of a study published in Cancer Prevention Research suggests a reduction in oral cancer.   

Green tea extract, taken orally among 41 patients, found 58.8% of patients at the highest doses showed a clinical response. Only 18.2% of patients taking a placebo showed a similar reponse.The study also found an improvement in several biomarkers, which might be important in charting potential cancer development.


  mercedes medical | innovation | green
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2009.11.20 21:13:51

From the New York Times article:

"Microscopes are invaluable tools to identify blood and other cells when screening for diseases like anemia, tuberculosis and malaria. But they are also bulky and expensive.

Now an engineer, using software that he developed and about $10 worth of off-the-shelf hardware, has adapted cellphones to substitute for microscopes.

... In one prototype, a slide holding a finger prick of blood can be inserted over the phone’s camera sensor. The sensor detects the slide’s contents and sends the information wirelessly to a hospital or regional health center. For instance, the phones can detect the asymmetric shape of diseased blood cells or other abnormal cells, or note an increase of white blood cells, a sign of infection..."

An amazing development for field work, and for care in less developed areas. This tool is even more useful because of the cellular phone it is built on. A doctor in the field can use the phone to send their microscopic imagery back to a lab, and then use it to receive results from a lab, without ever having to bring physical samples to a lab, or return to pick up results.

This technology uses light interference to create a 3-D hologram of the cells on a slide rather than passing light through it, so it reveals different features than a normal microscope. It seems from the article that the interior details of a cell are not visible with this type of microscope. The invention could still become an invaluable tool for early screening of parasitic diseases, spikes or decreases in blood cell count, and other diseases that affect the shape or quantity of cell structures.

Have any of our readers had any experience with this type of holographic blood scan? How about any training opportunities to study similar techniques?


  innovation | technology | microscopy | histology
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2009.11.12 03:27:10

TED talks are an annual conference for sharing revolutionary ideas and inventions with the scientific community at large. This year saw the addition of TEDMED, dedicated to innovations in the medical field, and Wired.com provided a great overview.

This year's talks were heavily centered around gadgets, digitization and how they might impact the future of medicine. Wireless monitoring technologies were shown off, a project to collect over 100,000 human genomes is off to a solid start, and living cultures of artificially grown tissue were passed around to attendees.

All in all, a great article on some phenomenal innovations. Read more for an excerpt from the article, or Click here to view it on Wired.com.


  news | technology | medical | innovation
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2009.11.10 20:26:38

Jessica Terry, 18 years old, discovered a telltale granuloma in one of her own pathology slides, leading to a successful diagnosis for a disease that had been a mystery to her doctors for years. Clearly a young histologist/pathologist in the making.

Glossed over in the article is the participation of the local, unnamed pathlogist who was working with her class to train them. I've never seen histology taught at a high school level before, but it definitely seems to have made a difference for at least one student. What are the thoughts of our histo readers? Would you be in favor of high school students getting a more advanced exposure to histology and medical education in general?

From the CNN Article

"For eight years, Jessica Terry suffered from stomach pain so horrible, it brought her to her knees. The pain, along with diarrhea, vomiting and fever, made her so sick, she lost weight and often had to miss school.

Her doctors, no matter how hard they tried, couldn't figure out the cause of Jessica's abdominal distress.

Then one day in January, Terry, 18, figured it out on her own."

Read the whole article at CNN.com


  news | education | histology
Comments 1 Hits: 571  

2009.11.10 00:10:38

Wired Science™ and Nikon™ hold an annual contest for the world's best microscopic photography, and this year's winners are truly amazing. There is a heavy slant towards flourescent or color enhanced microscopy for the vivid colors they produce, but there are some very nicely stained images in the historical winners categories.

From the Wired Science article:

" Winning the popular vote online out of 137 finalists was [this image]... by Dennis Breitsprecher of the Institute of Biophysical Chemistry at Germany’s Hannover Medical School." 

Read More at Wired Science

Do any of our readers enter this contest or have their own images they'd like to share with HistoWorld? Post them in the comments here!


  microscopy | contest | news | art | photography
Comments 0 Hits: 432  

2009.11.02 10:00:00

As some of our customers may know, Mercedes has an entire Mercedes Charity division. There are three main focuses in our giving. The first is donating medical supplies to nonprofit organizations. Our second focus is on animals and the third focus is the environment.


  charity | community | green | mercedes medical
Comments 0 Hits: 424